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Betz cells (also known as pyramidal cells of Betz) are giant () located within the fifth layer of the in the primary motor cortex. These neurons are the largest in the central nervous system, sometimes reaching 100 μm in diameter.

(2025). 9780878936977, Sinauer Associates.
Nolte, J. The Human Brain, 5th ed. Mosby: Missouri; 2002, p.527.

Betz cells are upper motor neurons that send their down to the via the tract, where in they directly with anterior horn cells, which in turn synapse directly with their target . Betz cells are not the sole source of direct connections to those neurons because most of the direct corticomotorneuronal cells are medium or small neurons. While Betz cells have one typical of pyramidal neurons, they have more primary dendritic shafts, which can branch out at almost any point from the soma (cell body). These perisomatic (around the cell body) and project into all cortical layers, but most of their horizontal branches/arbors populate layers V and VI, some reaching down into the . According to one study, Betz cells represent about 10% of the total pyramidal cell population in layer Vb of the human primary motor cortex.

Betz cells are named after Ukrainian scientist , who described them in his work published in 1874.Betz W. (1874) Anatomischer Nachweis zweier Gehirncentra. Centralblatt für die medizinischen Wissenschaften. 12:578-580, 595-599.


See also
List of distinct cell types in the adult human body


Notes

External links
  • Https://www.neuinfo.org/mynif/search.php?q=Betz%20Cell&t=data&s=cover&b=0&r=20" target="_blank" rel="nofollow"> NIF Search - Betz Cell via the Neuroscience Information Framework

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